Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcription factor ZNF148 is a negative regulator of human muscle differentiation.

Scientific reports - 15 Aug 2017

Bakke Jesse, Wright William C, Zamora Anthony E, Ong Su Sien, Wang Yue-Ming, Hoyer Jessica D, Brewer Christopher T, Thomas Paul G, Chen Taosheng

Abstract excerpt

Muscle differentiation is a complex process in which muscle progenitor cells undergo determination and eventually cellular fusion. This process is heavily regulated by such master transcription factors as MYOD and members of the MEF2 family. Here, we show that the transcription factor ZNF148 plays a direct role in human muscle cell differentiation. Downregulation of ZNF148 drives the formation of a muscle...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Cell Line, Transformed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockdown Techniques

Share to Muscle Development

Share to Muscle, Skeletal

Share to Myoblasts

Share to MyoD Protein

Share to RNA, Small Interfering

Source

Open in PubMed Open full text

Identifiers

PMID: 28811660
DOI: 10.1038/s41598-017-08267-5
PMCID: PMC5557752

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription factor ZNF148 is a negative regulator of human muscle differentiation.PMID 28811660Read ↗

Ccndbp1 is a new positive regulator of skeletal myogenesis.Semantic proximity Read ↗

The multifaceted role of MyoD in adult skeletal muscle: homeostasis, regeneration, and diseasesSemantic proximity Read ↗

ZNF865 Regulates Senescence and Cell Cycle for Applications to Cell Engineering and Gene TherapySemantic proximity Read ↗

DiPRO1 dependent transcriptional and epigenetic regulation distinctly controls the fate of muscle and mesenchymal cancer cellsSemantic proximity Read ↗

Regulation of HDAC9 gene expression by MEF2 establishes a negative-feedback loop in the transcriptional circuitry of muscle differentiation.Semantic proximity Read ↗

ZNF281/ZBP-99: a new player in epithelial–mesenchymal transition, stemness, and cancerSemantic proximity Read ↗

SRSF2 is a key player in orchestrating the directional migration and differentiation of MyoD progenitors during skeletal muscle developmentSemantic proximity Read ↗

Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle RegenerationSemantic proximity Read ↗

Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiationSemantic proximity Read ↗

Effects of HMGCR deficiency on skeletal muscle developmentSemantic proximity Read ↗

Postmitotic Expression of SOD1(G93A) Gene Affects the Identity of Myogenic Cells and Inhibits Myoblasts Differentiation.Semantic proximity Read ↗

Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.