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Article

Conformational modulation of influenza virus hemagglutinin: characterization and in vivo efficacy of monomeric form.

Scientific reports - 8 Aug 2017

Seok Jong Hyeon, Kim Jeongwon, Lee Dan Bi, Cho Ki Joon, Lee Ji-Hye, Bae Garam, Chung Mi Sook, Kim Kyung Hyun

Abstract excerpt

Mutational changes that mostly occur at the head region of hemagglutinin (HA) lead to the emergence of new epidemic influenza viruses, whereas HA antigens have been modified to generate broadly neutralizing antibodies toward highly conserved epitopes in the HA stem. Interestingly, a recent analysis of serum antibody repertoires showed that broadly neutralizing antibodies bind to HA monomer at a conserved region...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hemagglutinin Glycoproteins, Influenza Virus

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Identifiers

PMID: 28790432
DOI: 10.1038/s41598-017-08021-x
PMCID: PMC5548806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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