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Article

The antigenic architecture of the hemagglutinin of influenza H5N1 viruses.

Molecular immunology - 1 Dec 2013

Velkov Tony, Ong Chi, Baker Mark A, Kim Hyunsuh, Li Jian, Nation Roger L, Huang Johnny X, Cooper Matthew A, Rockman Steve

Abstract excerpt

Human infection with the highly pathogenic avian influenza A virus H5N1 is associated with a high mortality and morbidity. H5N1 continues to transmit from poultry to the human population, raising serious concerns about its pandemic potential. Current influenza H5N1 vaccines are based upon the elicitation of a neutralizing antibody (Ab) response against the major epitope regions of the viral surface glycoprotein,...

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Identifiers

PMID: 23933511
DOI: 10.1016/j.molimm.2013.07.010

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