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Article

Mutation of the TERT promoter leads to poor prognosis of patients with non-small cell lung cancer

31 May 2017

Abstract excerpt

Mutations in the promoter region of telomerase reverse transcriptase (TERT) and alterations in telomere length (TL) have been the focus of research in various types of cancer. In the present study, the frequency and clinical characteristics of TERT promoter mutations and TL were studied in non-small cell lung cancers (NSCLC). TERT promoter mutations and TL were analyzed in 188 patients using DNA sequencing and...

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PMID: 28789386
DOI: 10.3892/ol.2017.6284

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