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Article

TERT Polymorphism rs2736100-C Is Associated with EGFR Mutation-Positive Non-Small Cell Lung Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2015

Wei Rongrong, Cao Lan, Pu Hengying, Wang Hongwei, Zheng Yonglan, Niu Xiaomin, Weng Xiaoling, Zhang Hong, Favus Murray, Zhang Lanjun, Jia Weihua, Zeng Yixin, Amos Christopher I, Lu Shun, Wang Hui-Yun, Liu Yun, Liu Wanqing

Abstract excerpt

PURPOSE: EGF receptor (EGFR) mutation-positive (EGFRmut(+)) non-small cell lung cancer (NSCLC) may be a unique orphan disease. Previous studies suggested that the telomerase reverse transcriptase (TERT) gene polymorphism is associated with demographic and clinical features strongly associated with EGFR mutations, for example, adenocarcinoma histology, never-smoking history, and female gender. We aim to test the...

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Identifiers

PMID: 26149460
DOI: 10.1158/1078-0432.CCR-15-0009
PMCID: PMC4644673

Genes

EGFR
TERT
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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