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Article

Clinical Characteristics and Prognostic Significance of TERT Promoter Mutations in Cancer: A Cohort Study and a Meta-Analysis.

PloS one - 1 Jan 2016

Yuan Ping, Cao Jin-lin, Abuduwufuer Abudumailamu, Wang Lu-Ming, Yuan Xiao-Shuai, Lv Wang, Hu Jian

Abstract excerpt

BACKGROUND: The prevalence of telomerase reverse transcriptase (TERT) promoter mutations (pTERTm) in non-small-cell lung cancer (NSCLC) have been investigated, but the results were inconsistent. In addition, several studies have analysed the role of pTERTm in the etiology of various types of cancers, however, the results also remain inconsistent. METHODS: The genomic DNA sequence of 103 NSCLC samples were...

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Identifiers

PMID: 26799744
DOI: 10.1371/journal.pone.0146803
PMCID: PMC4723146

Genes

TERT

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