Article
Polymorphisms in the TERT gene are associated with lung cancer risk in the Chinese Han population.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Nov 2014
Gao Lei, Thakur Asmitananda, Liang Yiqian, Zhang Shuo, Wang Ting, Chen Tianjun, Meng Junhui, Wang Li, Wu Fang, Jin Tianbo, Li Xiaolan, Liu Johnson J, Chen Chao, Chen Mingwei
Abstract excerpt
Lung cancer has the highest mortality rate among cancers; however, its nosogenesis is still unclear. Genome-wide association studies have shown that the telomerase reverse transcriptase (TERT) gene, located in the chromosome 5p15.33 region, is one of the genes associated with the risk of lung cancer. In this case-control study, we genotyped 11 tag single-nucleotide polymorphisms of the TERT gene to evaluate their...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.