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Predicting outcomes of EGFR-targeted therapy in non-small cell lung cancer patients using pleural effusions samples and peptide nucleic acid probe assay.

Clinical chemistry and laboratory medicine - 26 Oct 2017

Wang Mei-Chia, Wang Chih-Liang, Chen Tai-Long, Chang John Wen-Cheng, Lu Jang-Jih, Chang Pi-Yueh, Chiou Chiuan-Chian

Abstract excerpt

BACKGROUND: Mutation of epidermal growth factor receptor (EGFR) is a prediction marker of the response to tyrosine kinase inhibitor (TKI) drugs in non-small cell lung cancer (NSCLC) patients. As late stage lung cancer patients rarely undergo surgery, samples for EGFR mutation identification usually come from computed tomography (CT)-guided or endoscopic biopsies, which is invasive and costly. Pleural effusion may...

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PMID: 28787267
DOI: 10.1515/cclm-2016-0809

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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