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Comparison of Epidermal Growth Factor Receptor Gene Mutations Identified Using Pleural Effusion and Primary Tumor Tissue Samples in Non-Small Cell Lung Cancer.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Apr 2018

Liu Nan, Sun Rui-Ze, Du Jiang, Dong Qian-Ze, Fan Chui-Feng, Li Qing-Chang, Wang En-Hua, Liu Yang

Abstract excerpt

BACKGROUND: Although the use of pleural effusion samples for epidermal growth factor receptor (EGFR) testing in lung cancer is increasing, the accuracy rate and effectiveness of identifying EGFR mutations using these samples, rather than primary tumor tissue samples, is not established. MATERIALS AND METHODS: One hundred ninety-two advanced, non-small cell lung cancer patients were enrolled into this study. All...

Topics

Adult
Aged
Aged, 80 and over
Carcinoma, Non-Small-Cell Lung
DNA Mutational Analysis
ErbB Receptors
Female
Humans
Lung Neoplasms
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mutation

Pleural Effusion

Retrospective Studies

Source

Identifiers

PMID: 28800007
DOI: 10.1097/PAI.0000000000000543

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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