Article
Improved detection of EGFR mutations in the tumor cells enriched from the malignant pleural effusion of non-small cell lung cancer patient.
Gene - 20 Feb 2018
Wang Yi, Liu Zhian, Yin Hanlu, Hu Jiahua, Zhong Shanliang, Chen Wenping, Zhao Jianhua
Abstract excerpt
Previous studies focus on developing high sensitive PCR-related technologies to detect EGFR gene mutation in malignant pleural effusion (MPE) of non-small cell lung cancer patient (NSCLC) instead of improving the quality of clinical samples themselves. We therefore hypothesized that the enrichment of tumor cells in MPE could improve the quality of MPE for the more accurate detection of EGFR gene mutation in the...
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