EGFR Mutation Status in Lung Adenocarcinoma-Associated Malignant Pleural Effusion and Efficacy of EGFR Tyrosine Kinase Inhibitors.

doi:10.4143/crt.2017.378

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Article

EGFR Mutation Status in Lung Adenocarcinoma-Associated Malignant Pleural Effusion and Efficacy of EGFR Tyrosine Kinase Inhibitors.

Cancer research and treatment - 1 Jul 2018

Yang Jiyoul, Lee Ok-Jun, Son Seung-Myoung, Woo Chang Gok, Jeong Yusook, Yang Yaewon, Kwon Jihyun, Lee Ki Hyeong, Han Hye Sook

Abstract excerpt

PURPOSE: Malignant pleural effusions (MPEs) are often observed in lung cancer, particularly adenocarcinoma. The aim of this study was to investigate epidermal growth factor receptor (EGFR) mutation status in lung adenocarcinoma-associated MPEs (LA-MPEs) and its correlation with efficacy of EGFR tyrosine kinase inhibitor (TKI) therapy. MATERIALS AND METHODS: Samples comprised 40 cell blocks of...

Topics

Adenocarcinoma
Adenocarcinoma of Lung
Adult
Aged
Aged, 80 and over
Disease Progression
ErbB Receptors
Female
Humans
Lung Neoplasms
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mutation

Pleural Effusion, Malignant

Protein Kinase Inhibitors

Retrospective Studies

Survival Analysis

Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 28934846
DOI: 10.4143/crt.2017.378
PMCID: PMC6056963

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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