Article
Characterization of Naturally Occurring NS5A and NS5B Polymorphisms in Patients Infected with HCV Genotype 3a Treated with Direct-Acting Antiviral Agents.
Viruses - 7 Aug 2017
Bartolini Barbara, Giombini Emanuela, Taibi Chiara, Lionetti Raffaella, Montalbano Marzia, Visco-Comandini Ubaldo, D'Offizi Gianpiero, Capobianchi Maria Rosaria, McPhee Fiona, Garbuglia Anna Rosa
Abstract excerpt
Hepatitis C virus (HCV) genotype (GT)3 is associated with increased risk of steatosis, development of cirrhosis and hepatocellular carcinoma. Limited data are available regarding genetic variability and use of direct-acting antiviral agents in these patients. non-structural protein 5A (NS5A) and non-structural protein 5B (NS5B) sequencing was performed on 45 HCV GT3-infected Italian patients subsequently treated...
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