Article
β-Sarcoglycan Deficiency Reduces Atherosclerotic Plaque Development in ApoE-Null Mice.
Journal of vascular research - 1 Jan 2017
Murugesan Vignesh, Degerman Eva, Holmen-Pålbrink Ann-Kristin, Duner Pontus, Knutsson Anki, Hultgårdh-Nilsson Anna, Rauch Uwe
Abstract excerpt
BACKGROUND: Smooth muscle cells are important for atherosclerotic plaque stability. Their proper ability to communicate with the extracellular matrix is crucial for maintaining the correct tissue integrity. In this study, we have investigated the role of β-sarcoglycan within the matrix-binding dystrophin-glycoprotein complex in the development of atherosclerosis. RESULTS: Atherosclerotic plaque development was...
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