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Article

Genetic variability and functional implication of the long control region in HPV-16 variants in Southwest China.

PloS one - 1 Jan 2017

Xi Juemin, Chen Junying, Xu Miaoling, Yang Hongying, Luo Jia, Pan Yue, Wang Xiaodan, Qiu Lijuan, Yang Jiajia, Sun Qiangming

Abstract excerpt

HPV-16 long control region (LCR) has been shown to be the most variable region of the HPV-16 genome and may play important roles in viral persistence and the development of cervical cancer. This study aimed to assess the risk of HPV-16 LCR variants for cervical cancer in women of Southwest China. 2146 cervical scrapings of volunteer outpatients and 74 cervical cancer tissues were screened.14 entire HPV-16 LCRs...

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Source

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Identifiers

PMID: 28767682
DOI: 10.1371/journal.pone.0182388
PMCID: PMC5540483

Genes

FOXA1
SOX9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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