Article
Genetic variability, phylogeny and functional implication of the long control region in human papillomavirus type 16, 18 and 58 in Chengdu, China.
Virology journal - 16 Jul 2020
Fang Liyuan, Lin Xiaoli, Yang Yasi, Song Zhilin, Ding Xianping, Tan Liping, Gao Peng
Abstract excerpt
BACKGROUND: Long control region (LCR) of human papillomavirus (HPV) has shown multiple functions on regulating viral transcription. The variations of LCR related to different lineages/sub-lineages have been found to affect viral persistence and cervical cancer progression differently. In this study, we focused on gene polymorphism of HPV16/18/58 LCR to assess the effect variations caused on transcription factor...
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