Human papillomavirus type 16 variant analysis of E6, E7, and L1 genes and long control region in biopsy samples from cervical cancer patients in north India.

doi:10.1128/JCM.02202-07

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Article

Human papillomavirus type 16 variant analysis of E6, E7, and L1 genes and long control region in biopsy samples from cervical cancer patients in north India.

Journal of clinical microbiology - 1 Mar 2008

Pande Shailja, Jain Neeraj, Prusty Bhupesh K, Bhambhani Suresh, Gupta Sanjay, Sharma Rajyashri, Batra Swaraj, Das Bhudev C

Abstract excerpt

High-risk human papillomaviruses (HPVs), particularly HPV types 16 and 18 (HPV-16 and HPV-18, respectively), play a cardinal role in the etiology of cervical cancer. The most prevalent type, HPV-16, shows intratypic sequence variants that are known to differ in oncogenic potential and geographic distribution. This study was designed to analyze sequence variations in E6, E7, and L1 genes and the LCR (for long...

Topics

Base Sequence
Biopsy
Capsid Proteins
DNA, Viral
Female
Genetic Variation
Human papillomavirus 16
Humans
India
Locus Control Region
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oncogene Proteins, Viral

Papillomavirus E7 Proteins

Papillomavirus Infections

Polymerase Chain Reaction

Repressor Proteins

Sequence Analysis, DNA

Uterine Cervical Neoplasms

Source

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Identifiers

PMID: 18199779
DOI: 10.1128/JCM.02202-07
PMCID: PMC2268386

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