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Human Papillomavirus Type 16 E1 Mutations Associated with Cervical Cancer in a Han Chinese Population

1 Jan 2019

Abstract excerpt

Human papillomavirus type 16 (HPV16) is a high-risk HPV type and a potent carcinogen. HPV E1 is one of the most highly conserved proteins and it plays a central role in initiating HPV DNA replication. In current study, we enrolled 161 HPV16-positive cervical cancer patients (case group) and 171 HPV16-positive asymptomatic individuals (control group) in a study to analyse the association between HPV16 E1 genetic...

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PMID: 31341418
DOI: 10.7150/ijms.34279

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