Article
Genetic diversity and functional implication of the long control region in human papillomavirus types 52, 58, and 16 from Central China.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2023
Yang ZhiPing, Zhang Chunlin, Luo Ping, Sun Fenglan, Mei Bing
Abstract excerpt
OBJECT: High-risk human papillomavirus (HR-HPV) is a main reason for cervical cancer. The long control region (LCR) of the genome plays a variety of roles in the transcription of the virus. METHODS: LCR sequences were amplified by polymerase chain reaction (PCR) and confirmed by DNA sequencing. MEGA 11.0 software and NCBI blast were used to analyze the sequences and construct the Neighbor-Joining tree. In...
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