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Article

The peroxisomal matrix protein translocon is a large cavity-forming protein assembly into which PEX5 protein enters to release its cargo.

The Journal of biological chemistry - 15 Sept 2017

Dias Ana F, Rodrigues Tony A, Pedrosa Ana G, Barros-Barbosa Aurora, Francisco Tânia, Azevedo Jorge E

Abstract excerpt

A remarkable property of the machinery for import of peroxisomal matrix proteins is that it can accept already folded proteins as substrates. This import involves binding of newly synthesized proteins by cytosolic peroxisomal biogenesis factor 5 (PEX5) followed by insertion of the PEX5-cargo complex into the peroxisomal membrane at the docking/translocation module (DTM). However, how these processes occur remains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28765278
DOI: 10.1074/jbc.M117.805044
PMCID: PMC5602389

Genes

PEX5
PEX14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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