Article

A novel PEX14/PEX5 interface links peroxisomal protein import and receptor recycling

2023-08-09

Abstract excerpt

Newly synthesized peroxisomal proteins are recognized in the cytosol by the cycling receptor PEX5 and directed to a docking complex comprising PEX14 and PEX13 at the peroxisomal membrane. After cargo translocation, the unloaded PEX5 is recycled in an ATP-dependent manner. Receptor docking involves the WxxxF-motifs in the N-terminal domain (NTD) of PEX5 that are recognized by the N-terminal domain of PEX14. Here, w...

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Literature Corpus work: 42dda413-f9e7-52da-925e-772ff90bcc3d
DOI: 10.1101/2023.08.08.552478

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