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Clinico-genomic study reveals association of dengue virus genome high frequency mutations with dengue disease severity

28 May 2025

Abstract excerpt

Transmission of the dengue virus (DENV) places a huge burden on public health in several endemic regions. Like other RNA viruses, mutations in the DENV genome greatly governs its virulence, transmissibility, and interaction with the host immune system. Present study focuses on integrated analysis of mutation and clinical data accompanied at the onset of dengue fever. The findings from the associated clinical data...

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PMID: 40436903
DOI: 10.1038/s41598-025-00462-z

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