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Article

Krox20 hindbrain regulation incorporates multiple modes of cooperation between cis-acting elements.

PLoS genetics - 1 Jul 2017

Thierion Elodie, Le Men Johan, Collombet Samuel, Hernandez Céline, Coulpier Fanny, Torbey Patrick, Thomas-Chollier Morgane, Noordermeer Daan, Charnay Patrick, Gilardi-Hebenstreit Pascale

Abstract excerpt

Developmental genes can harbour multiple transcriptional enhancers that act simultaneously or in succession to achieve robust and precise spatiotemporal expression. However, the mechanisms underlying cooperation between cis-acting elements are poorly documented, notably in vertebrates. The mouse gene Krox20 encodes a transcription factor required for the specification of two segments (rhombomeres) of the...

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Identifiers

PMID: 28749941
DOI: 10.1371/journal.pgen.1006903
PMCID: PMC5549768

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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