Article
Krox20 controls the transcription of its various targets in the developing hindbrain according to multiple modes.
The Journal of biological chemistry - 17 Apr 2009
Desmazières Anne, Charnay Patrick, Gilardi-Hebenstreit Pascale
Abstract excerpt
The zinc finger transcription factor Krox20 plays an essential role in the vertebrate hindbrain segmentation process. It positively or negatively controls a large variety of other regulatory genes, coordinating delimitation of segmental territories, specification of their identity, and maintenance of their integrity. We have investigated the molecular mechanisms of Krox20 transcriptional control by performing a...
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