Article
Segmental expression of Hoxa-2 in the hindbrain is directly regulated by Krox-20.
Development (Cambridge, England) - 1 Feb 1996
Nonchev S, Vesque C, Maconochie M, Seitanidou T, Ariza-McNaughton L, Frain M, Marshall H, Sham M H, Krumlauf R, Charnay P
Abstract excerpt
The hindbrain is a segmented structure divided into repeating metameric units termed rhombomeres (r). The Hox family, vertebrate homologs of the Drosophila HOM-C homeotic selector genes, are expressed in rhombomere-restricted patterns and are believed to participate in regulating segmental identities. Krox-20, a zinc finger gene, has a highly conserved pattern of expression in r3 and r5 and is functionally...
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