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Article

Copy Number Changes Identified Using Whole Exome Sequencing in Nonsyndromic Cleft Lip and Palate in a Honduran Population.

Birth defects research - 2 Oct 2017

Cai Yi, Patterson Karynne E, Reinier Frederic, Keesecker Sarah E, Blue Elizabeth, Bamshad Michael, Haddad Joseph

Abstract excerpt

BACKGROUND: The majority of cleft lip with or without cleft palate cases appear as an isolated, nonsyndromic entity (NSCLP). With the advent of next generation sequencing, whole exome sequencing (WES) has been used to identify single nucleotide variants and insertion/deletions which cause or increase the risk of NSCLP. However, to our knowledge, there are no published studies using WES in NSCLP to investigate...

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Open in PubMed Open full text

Identifiers

PMID: 28748635
DOI: 10.1002/bdr2.1063
PMCID: PMC5854563

Genes

ADH7
AHR
CRYZ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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