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Article

Exome Sequencing Studies in Syndromic Patients With Cleft Lip and/or Palate: Systematic Review.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jul 2026

Cárdenas-Nieto Diana, Briceño-Balcázar Ignacio, Martínez-Lozano Julio, Rondón-Lagos Milena, Forero-Castro Maribel

Abstract excerpt

ObjectiveThe etiology of syndromic cleft lip and/or cleft palate (CL/P) is multifactorial and polygenic. This study aims to identify genetic variants diagnosed by exome sequencing and present in this type of patients.DesignSystematic review.MethodsA systematic review was performed according to the PRISMA guidelines in the PubMed database including the terms "cleft palate," "cleft lip," "cleft lip and palate,"...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40611759
DOI: 10.1177/10556656251355782

Genes

CHD7
MEIS2
SATB2
TP63

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Exome Sequencing Studies in Syndromic Patients With Cleft Lip and/or Palate: Systematic Review.PMID 40611759Read ↗

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Distinct genetic architecture and multiple omics features between non-syndromic cleft lip only and non-syndromic cleft lip with cleft palateSemantic proximity Read ↗

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