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Article

Identification of susceptibility genes in non-syndromic cleft lip with or without cleft palate using whole-exome sequencing.

Medicina oral, patologia oral y cirugia bucal - 1 Nov 2015

Liu Ya-Peng, Xu Li-Fang, Wang Qi, Zhou Xiao-Long, Zhou Ji-Long, Pan Chen, Zhang Jin-Peng, Wu Qin-Rong, Li Yi-Qun, Xia Yu-Juan, Peng Xiu, Zhang Mei-Rong, Yu Hong-Min, Xu Li-Chun

Abstract excerpt

BACKGROUND: Non-syndromic cleft lip with or without cleft palate (NSCL/P) is among the most common congenital malformations. The etiology of NSCL/P remains poorly characterized owing to its complex genetic heterogeneity. The objective of this study was to identify genetic variants that increase susceptibility to NSCL/P. MATERIAL AND METHODS: Whole-exome sequencing (WES) was performed in 8 fetuses with NSCL/P in...

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Identifiers

PMID: 26449438
DOI: 10.4317/medoral.20758
PMCID: PMC4670259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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