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Article

Deleterious coding variants in multi-case families with non-syndromic cleft lip and/or palate phenotypes.

Scientific reports - 26 Jul 2016

Pengelly Reuben J, Arias Liliana, Martínez Julio, Upstill-Goddard Rosanna, Seaby Eleanor G, Gibson Jane, Ennis Sarah, Collins Andrew, Briceño Ignacio

Abstract excerpt

Nonsyndromic Cleft Lip and/or Palate (NSCLP) is regarded as a multifactorial condition in which clefting is an isolated phenotype, distinguished from the largely monogenic, syndromic forms which include clefts among a spectrum of phenotypes. Nonsyndromic clefting has been shown to arise through complex interactions between genetic and environmental factors. However, there is increasing evidence that the broad...

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Identifiers

PMID: 27456059
DOI: 10.1038/srep30457
PMCID: PMC4960602

Genes

MSX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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