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Article

Using Whole Exome Sequencing to Identify Candidate Genes With Rare Variants In Nonsyndromic Cleft Lip and Palate.

Genetic epidemiology - 1 Jul 2016

Aylward Alana, Cai Yi, Lee Andrew, Blue Elizabeth, Rabinowitz Daniel, Haddad Joseph

Abstract excerpt

Studies suggest that nonsyndromic cleft lip and palate (NSCLP) is polygenic with variable penetrance, presenting a challenge in identifying all causal genetic variants. Despite relatively high prevalence of NSCLP among Amerindian populations, no large whole exome sequencing (WES) studies have been completed in this population. Our goal was to identify candidate genes with rare genetic variants for NSCLP in a...

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Identifiers

PMID: 27229527
DOI: 10.1002/gepi.21972
PMCID: PMC4985012

Genes

ACSS2
PHYH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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