Article
Genome-wide assessment for genetic variants associated with ventricular dysfunction after primary coronary artery bypass graft surgery.
PloS one - 1 Jan 2011
Fox Amanda A, Pretorius Mias, Liu Kuang-Yu, Collard Charles D, Perry Tjorvi E, Shernan Stanton K, De Jager Philip L, Hafler David A, Herman Daniel S, DePalma Steven R, Roden Dan M, Muehlschlegel Jochen D, Donahue Brian S, Darbar Dawood, Seidman J G, Body Simon C, Seidman Christine E
Abstract excerpt
BACKGROUND: Postoperative ventricular dysfunction (VnD) occurs in 9-20% of coronary artery bypass graft (CABG) surgical patients and is associated with increased postoperative morbidity and mortality. Understanding genetic causes of postoperative VnD should enhance patient risk stratification and improve treatment and prevention strategies. We aimed to determine if genetic variants associate with occurrence of...
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