Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA Double-Strand Break Repair Assay.

Cold Spring Harbor protocols - 2 Apr 2018

Pai Chen-Chun, Blaikley Elizabeth, Humphrey Timothy C

Abstract excerpt

DNA double-strand breaks (DSBs), arising during normal DNA metabolism or following exposure to mutagenic agents such as ionizing radiation can lead to chromosomal rearrangements and genome instability, and are potentially lethal if unrepaired. Therefore, understanding the mechanisms of DSB repair and misrepair, and identifying the factors involved in these processes is of biological as well as medical interest....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Assay
Share to Cell Survival
Share to Chromosomes, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crosses, Genetic

Share to DNA Breaks, Double-Stranded

Share to DNA Repair

Share to Schizosaccharomyces

Share to Transformation, Genetic

Source

Identifiers

PMID: 28733408
DOI: 10.1101/pdb.prot092031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA Double-Strand Break Repair Assay.PMID 28733408Read ↗

Pathway utilization in response to a site-specific DNA double-strand break in fission yeast.Semantic proximity Read ↗

DNA double-strand breaks in meiosis: Checking their formation, processing and repairSemantic proximity Read ↗

DNA single-strand break repairSemantic proximity Read ↗

Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.Semantic proximity Read ↗

Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.Semantic proximity Read ↗

Break-induced replication forms long mutable single-strand DNA during meiosis.Semantic proximity Read ↗

Physical and Genetic Assays for the Study of DNA Joint Molecules Metabolism and Multi-invasion-Induced Rearrangements in S. cerevisiae.Semantic proximity Read ↗

Pathway choice in DNA double strand break repair: observations of a balancing actSemantic proximity Read ↗

Systematic Identification of Determinants for Single-Strand Annealing-Mediated Deletion Formation in Saccharomyces cerevisiae.Semantic proximity Read ↗

DNA repair functions that control sensitivity to topoisomerase-targeting drugs.Semantic proximity Read ↗

Proofreading activity of DNA polymerase Pol2 mediates 3'-end processing during nonhomologous end joining in yeast.Semantic proximity Read ↗

Mutant cells defective in DNA repair pathways provide a sensitive high-throughput assay for genotoxicity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.