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Article

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging

21 Jul 2017

Abstract excerpt

BACKGROUND: The necessity of including both males and females in molecular neuroscience research is now well understood. However, there is relatively limited basic biological data on brain sex differences across the lifespan despite the differences in age-related neurological dysfunction and disease between males and females. METHODS: Whole genome gene expression of young (3 months), adult (12 months), and old...

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PMID: 28732515
DOI: 10.1186/s12974-017-0920-8

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