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Article

Stim1 Regulates Enamel Mineralization and Ameloblast Modulation.

Journal of dental research - 1 Nov 2017

Furukawa Y, Haruyama N, Nikaido M, Nakanishi M, Ryu N, Oh-Hora M, Kuremoto K, Yoshizaki K, Takano Y, Takahashi I

Abstract excerpt

Loss-of-function mutations in the Ca2+ release-activated Ca2+ channel genes ORAI1 and STIM1 abolish store-operated Ca2+ entry (SOCE) and result in ectodermal dysplasia with amelogenesis imperfecta. However, because of the limited availability of patient tissue, analyses of enamel mineralization or possible changes in ameloblast function or morphology have not been possible. Here, we generated mice with ectodermal...

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Share to Amelogenesis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Stromal Interaction Molecule 1

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Source

Identifiers

PMID: 28732182
DOI: 10.1177/0022034517719872

Genes

ORAI1
STIM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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