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Article

STIM1 R304W in mice causes subgingival hair growth and an increased fraction of trabecular bone.

Cell calcium - 1 Jan 2020

Gamage Thilini H, Lengle Emma, Gunnes Gjermund, Pullisaar Helen, Holmgren Asbjørn, Reseland Janne E, Merckoll Else, Corti Stefania, Mizobuchi Masahiro, Morales Raul J, Tsiokas Leonidas, Tjønnfjord Geir E, Lacruz Rodrigo S, Lyngstadaas Staale P, Misceo Doriana, Frengen Eirik

Abstract excerpt

Calcium signaling plays a central role in bone development and homeostasis. Store operated calcium entry (SOCE) is an important calcium influx pathway mediated by calcium release activated calcium (CRAC) channels in the plasma membrane. Stromal interaction molecule 1 (STIM1) is an endoplasmic reticulum calcium sensing protein important for SOCE. We generated a mouse model expressing the STIM1 R304W mutation,...

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Identifiers

PMID: 31785581
DOI: 10.1016/j.ceca.2019.102110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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