Article
STIM1 and SLC24A4 Are Critical for Enamel Maturation.
Journal of dental research - 1 Jul 2014
Wang S, Choi M, Richardson A S, Reid B M, Seymen F, Yildirim M, Tuna E, Gençay K, Simmer J P, Hu J C
Abstract excerpt
Dental enamel formation depends upon the transcellular transport of Ca(2+) by ameloblasts, but little is known about the molecular mechanism, or even if the same process is operative during the secretory and maturation stages of amelogenesis. Identifying mutations in genes involved in Ca(2+) homeostasis that cause inherited enamel defects can provide insights into the molecular participants and potential...
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