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Article

Absence of transforming growth factor beta 1 in murine platelets reduces neointima formation without affecting arterial thrombosis.

Thrombosis and haemostasis - 31 Aug 2017

Schütz Eva, Bochenek Magdalena L, Riehl Dennis R, Bosmann Markus, Münzel Thomas, Konstantinides Stavros, Schäfer Katrin

Abstract excerpt

Platelet degranulation at the site of vascular injury prevents bleeding and may affect the chronic vascular wound healing response. Transforming Growth Factor (TGF)-β1 is a major component of platelet α-granules known to accumulating in thrombi. It was our aim to determine the role of TGFβ1 released from activated platelets for neointima formation following arterial injury and thrombosis. Mice with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28726976
DOI: 10.1160/TH17-02-0112

Genes

MMP2
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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