Article
Molecular Characterization of Mycobacterium tuberculosis Strains with TB-SPRINT.
The American journal of tropical medicine and hygiene - 1 Sept 2017
Molina-Moya Barbara, Gomgnimbou Michel Kiréopori, Lafoz Carmen, Lacoma Alicia, Prat Cristina, Refrégier Guislaine, Samper Sofia, Dominguez Jose, Sola Christophe
Abstract excerpt
We evaluated Tuberculosis-Spoligo-Rifampicin-Isoniazid Typing (TB-SPRINT), a microbead-based method for spoligotyping and detection of rifampicin and isoniazid resistance in Mycobacterium tuberculosis. For that, 67 M. tuberculosis complex strains were retrospectively selected. Membrane-based spoligotyping, restriction fragment length polymorphism, DNA sequencing/pyrosequencing of rpoB, katG, and inhA promoter,...
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