Article
TB-EFI, a novel 18-Plex microbead-based method for prediction of second-line drugs and ethambutol resistance in Mycobacterium tuberculosis complex.
Journal of microbiological methods - 1 Sept 2018
Klotoe Bernice J, Molina-Moya Barbara, Gomes Harrison Magdinier, Gomgnimbou Michel K, Oliveira Suzarte Lorenna, Féres Saad Maria H, Ali Sajid, Dominguez José, Pimkina Edita, Zholdybayeva Elena, Sola Christophe, Refrégier Guislaine
Abstract excerpt
Several diagnostic tests are being developed to detect drug resistance in tuberculosis. In line with previous developments detecting rifampicin and isoniazid resistance using microbead-based systems (spoligoriftyping and TB-SPRINT), we present here an assay called TB-EFI detecting mutations involved in resistance to ethambutol, fluoroquinolones and the three classical injectable drugs (kanamycin, amikacin and...
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