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Article

Association of clinical severity of cystic fibrosis with variants in the SLC gene family (SLC6A14, SLC26A9, SLC11A1 and SLC9A3).

Gene - 20 Sept 2017

Pereira Stéphanie Villa-Nova, Ribeiro José Dirceu, Bertuzzo Carmen Sílvia, Marson Fernando Augusto Lima

Abstract excerpt

INTRODUCTION: Cystic fibrosis (CF) manifests with clinical and histopathological variability depending on environmental and genetic factors. Moreover, the genes encoding ion channels[rs3788766(SLC6A14), rs7512462(SLC26A9), rs17235416(SLC11A1) and rs17563161(SLC9A3)] have been insufficiently studied as modifier genes. Then, our objective was associate the variants in the genes of SLC family with 43 CF severity...

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Share to Bacterial biofilms and quorum sensing
Share to Cystic Fibrosis
Share to Cystic Fibrosis Research Advances
Share to Cystic Fibrosis Transmembrane Conductance Regulator
Share to CFTR gene
Share to Ion Transport and Channel Regulation
Share to Polymorphism, Single Nucleotide
Share to Real-Time Polymerase Chain Reaction

Source

Identifiers

PMID: 28756021
DOI: 10.1016/j.gene.2017.07.068

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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