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Article

Influence of L-dopa on subtle motor signs in heterozygous Parkin- and PINK1 mutation carriers.

Parkinsonism & related disorders - 1 Sept 2017

Weissbach Anne, König Inke R, Hückelheim Katja, Pramstaller Peter P, Werner Elisa, Brüggemann Norbert, Tadic Vera, Lohmann Katja, Bäumer Tobias, Münchau Alexander, Kasten Meike, Klein Christine

Abstract excerpt

INTRODUCTION: A latent nigrostriatal deficit and its possible clinical consequences in asymptomatic heterozygous Parkin and PINK1 mutation carriers (AMC) have been a matter of investigation in recent years. Notably, mild Parkinsonian signs in heterozygous mutation carriers can be so subtle that they may be missed if not specifically investigated. METHODS: We studied 15 heterozygous Parkin and PINK1 AMC and 18...

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Source

Identifiers

PMID: 28716427
DOI: 10.1016/j.parkreldis.2017.07.003

Genes

PINK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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