Article
The RhoGAP crossveinless-c interacts with Dystrophin and is required for synaptic homeostasis at the Drosophila neuromuscular junction.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 12 Jan 2011
Pilgram Gonneke S K, Potikanond Saranyapin, van der Plas Mariska C, Fradkin Lee G, Noordermeer Jasprina N
Abstract excerpt
Duchenne muscular dystrophy is caused by mutations in the Dystrophin gene and is characterized by muscle degeneration and the occurrence of mental deficits in a significant number of patients. Although Dystrophin and its closely related ortholog Utrophin are present at a variety of synapses, little is known about their roles in the nervous system. Previously, we reported that absence of postsynaptic Dystrophin...
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