Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

UNC-6/netrin and its receptor UNC-5 locally exclude presynaptic components from dendrites.

Nature - 2 Oct 2008

Poon Vivian Y, Klassen Matthew P, Shen Kang

Abstract excerpt

Polarity is an essential feature of many cell types, including neurons that receive information from local inputs within their dendrites and propagate nerve impulses to distant targets through a single axon. It is generally believed that intrinsic structural differences between axons and dendrite...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans Proteins
Share to Dendrites
Share to Glycoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Presynaptic Terminals

Share to rab3 GTP-Binding Proteins

Share to Receptors, Cell Surface

Share to Synapses

Share to Wnt Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 18776887
DOI: 10.1038/nature07291
PMCID: PMC3912858

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18776887-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

UNC-6/netrin and its receptor UNC-5 locally exclude presynaptic components from dendrites.PMID 18776887Read ↗

UNC-6/netrin and its receptors UNC-5 and UNC-40/DCC modulate growth cone protrusion in vivo in C. elegans.Semantic proximity Read ↗

ENU-3 functions in an UNC-6/netrin dependent pathway parallel to UNC-40/DCC/frazzled for outgrowth and guidance of the touch receptor neurons in C. elegans.Semantic proximity Read ↗

Netrin (UNC-6) mediates dendritic self-avoidance.Semantic proximity Read ↗

Extracellular matrix regulates UNC-6 (netrin) axon guidance by controlling the direction of intracellular UNC-40 (DCC) outgrowth activity.Semantic proximity Read ↗

Identification of domains of netrin UNC-6 that mediate attractive and repulsive guidance and responses from cells and growth cones.Semantic proximity Read ↗

RPM-1, a Caenorhabditis elegans protein that functions in presynaptic differentiation, negatively regulates axon outgrowth by controlling SAX-3/robo and UNC-5/UNC5 activity.Semantic proximity Read ↗

Inhibition of netrin-mediated axon attraction by a receptor protein tyrosine phosphatase.Semantic proximity Read ↗

MIG-10/lamellipodin and AGE-1/PI3K promote axon guidance and outgrowth in response to slit and netrin.Semantic proximity Read ↗

The conserved kinase UNC-51 acts with VAB-8 and UNC-14 to regulate axon outgrowth in C. elegans.Semantic proximity Read ↗

A conserved juxtacrine signal regulates synaptic partner recognition in Caenorhabditis elegans.Semantic proximity Read ↗

Shared receptors in axon guidance: SAX-3/Robo signals via UNC-34/Enabled and a Netrin-independent UNC-40/DCC function.Semantic proximity Read ↗

An UNC-40 pathway directs postsynaptic membrane extension in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.