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Article

BAR-SH3 sorting nexins are conserved interacting proteins of Nervous wreck that organize synapses and promote neurotransmission.

Journal of cell science - 1 Jan 2016

Ukken Fiona P, Bruckner Joseph J, Weir Kurt L, Hope Sarah J, Sison Samantha L, Birschbach Ryan M, Hicks Lawrence, Taylor Kendra L, Dent Erik W, Gonsalvez Graydon B, O'Connor-Giles Kate M

Abstract excerpt

Nervous wreck (Nwk) is a conserved F-BAR protein that attenuates synaptic growth and promotes synaptic function in Drosophila. In an effort to understand how Nwk carries out its dual roles, we isolated interacting proteins using mass spectrometry. We report a conserved interaction between Nwk proteins and BAR-SH3 sorting nexins, a family of membrane-binding proteins implicated in diverse intracellular trafficking...

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Identifiers

PMID: 26567222
DOI: 10.1242/jcs.178699
PMCID: PMC4732300

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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