Article
Neurexin mediates the assembly of presynaptic terminals.
Nature neuroscience - 1 Jul 2003
Dean Camin, Scholl Francisco G, Choih Jenny, DeMaria Shannon, Berger James, Isacoff Ehud, Scheiffele Peter
Abstract excerpt
Neurexins are a large family of proteins that act as neuronal cell-surface receptors. The function and localization of the various neurexins, however, have not yet been clarified. Beta-neurexins are candidate receptors for neuroligin-1, a postsynaptic membrane protein that can trigger synapse formation at axon contacts. Here we report that neurexins are concentrated at synapses and that purified neuroligin is...
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