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Article

CKAP2 phosphorylation by CDK1/cyclinB1 is crucial for maintaining centrosome integrity.

Experimental & molecular medicine - 14 Jul 2017

Yoo Bum Ho, Kang Du-Seock, Park Chi-Hu, Kang Kyeongjin, Bae Chang-Dae

Abstract excerpt

Previously, we have reported that CKAP2 is involved in the maintenance of centrosome integrity, thus allowing for proper mitosis in primary hepatocytes. To understand this biological process, we identified the mitosis-specific phosphorylation sites in mouse CKAP2 and investigated CKAP's possible role in cell cycle progression. Because we observed mouse CKAP2 depletion in amplified centrosomes and aberrant...

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Share to CDC2 Protein Kinase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Segregation

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Source

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Identifiers

PMID: 28706298
DOI: 10.1038/emm.2017.92
PMCID: PMC5565958

Genes

CKAP2
CDK1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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