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Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model

20 Jul 2017

Abstract excerpt

Tuberculosis remains one of the major threats to public health worldwide. Given the prevalence of multi drug resistance (MDR) in Mycobacterium tuberculosis strains, there is a strong need to develop new anti-mycobacterial drugs with modes of action distinct from classical antibiotics. Inhibitors of mycobacterial virulence might target new molecular processes and may represent a potential new therapeutic...

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PMID: 28727774
DOI: 10.1371/journal.pone.0181121

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