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Article

Identification of Mycobacterium marinum virulence genes using signature-tagged mutagenesis and the goldfish model of mycobacterial pathogenesis.

FEMS microbiology letters - 12 Mar 2004

Ruley Kristin M, Ansede John H, Pritchett Christopher L, Talaat Adel M, Reimschuessel Renate, Trucksis Michele

Abstract excerpt

Mycobacterium marinum, a causative agent of fish tuberculosis, is one of the most closely related Mycobacterium species (outside the M. tuberculosis complex) to M. tuberculosis, the etiologic agent of human tuberculosis. Signature-tagged mutagenesis was used to identify genes of M. marinum required for in vivo survival in a goldfish model of mycobacterial pathogenesis. Screening the first 1008 M. marinum mutants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15019737
DOI: 10.1016/S0378-1097(04)00017-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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