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Article

Dictyostelium AMPKα regulates aggregate size and cell-type patterning.

Open biology - 1 Jul 2017

Maurya Ranjana, Kumar Rakesh, Saran Shweta

Abstract excerpt

Starved Dictyostelium cells aggregate into groups of nearly 105 cells. AMPK is a highly conserved serine/threonine protein kinase consisting of a catalytic and two regulatory subunits. As multi-cellular development in Dictyostelium is initiated upon starvation, we explored the role of the energy sensor, AMPK, which shows significant similarity to human AMPK and is expressed throughout development. Deletion of the...

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Identifiers

PMID: 28701378
DOI: 10.1098/rsob.170055
PMCID: PMC5541345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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