Article
AMPK phosphorylation by Ssp1 is required for proper sexual differentiation in fission yeast.
Journal of cell science - 1 Jun 2012
Valbuena Noelia, Moreno Sergio
Abstract excerpt
The AMP-activated protein kinase (AMPK) is a central regulator of cellular energy homeostasis, which, in response to a fall in intracellular ATP levels, activates energy-producing pathways and inhibits energy-consuming processes. Here, we report that fission yeast cells lacking AMPK activity are unable to advance entry into mitosis in response to nitrogen starvation and cannot undergo proper G1 arrest and cell...
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