AMP-activated protein kinase: A key enzyme to manage nutritional stress responses in parasites with complex life cycles

Abstract excerpt

Trypanosoma cruzi , the etiological agent of Chagas disease, has a digenetic life cycle. In its passage from the insect vector to the mammalian host, and vice versa, it must be prepared to cope with abrupt changes in environmental conditions in order to survive. Sensing and signaling pathways that allow the parasite to adapt, have unique characteristics with respect to their hosts and other free-living organisms....

Topics

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• Autophagy in Disease and Therapy
• Biochemical and Molecular Research
• Endoplasmic Reticulum Stress and Disease
• Metabolism, Diabetes, and Cancer
• Pancreatic function and diabetes
• Research on Leishmaniasis Studies
• Toxoplasma gondii Research Studies
• Trypanosoma species research and implications

Identifiers and source

Literature Corpus work

5a5b1c28-dc53-5f0e-bc5f-3a2ec2933331

DOI

10.1101/2020.04.08.032284